05). Those with the answer “”when prescribing antibiotics, I pay attention to the patient’s clinical condition”" are the highest among physicians who were employed by private sector (p<0.05). A further study is suggested at this point, AZD9291 aiming to find out underlying reasons. Considering that this topic, the rational use of antibiotics, is being used in various symposiums and scientific activities in recent years, this study suggests we should keep paying the same attention on this scientific matter. At least, carrying out in-service trainings is suggested. Also suggested could
be conducting similar researches on the fields other than pediatrics.”
“Study Design. Retrospective review of a single tertiary care spine database to identify patients with C2 instrumentation between January 2001 and September 2008.
Objective. MK-1775 (1) Evaluate a large series of posterior C2 screws to determine accuracy by computed tomography (CT) scan, (2) assess dimensions of “”safe bony windows”" with CT, and (3) assess perioperative complication rate related to errant screw
placement.
Summary of Background Data. The variable C2 anatomy can make instrumentation challenging and prone to potentially severe complications. New techniques have expanded available options.
Methods. Clinical data were obtained from the medical record. Radiographic analyses included preoperative and postoperative CT scans to quantify the patients’ bone and to classify accuracy of instrumentation. Screws were graded using the following definitions:
Type I: Screw threads completely within the bone.
Type II: Less than (1/2) the diameter of the screw violates the surrounding cortex.
Type III: Clear violation of transverse foramen or spinal canal.
Results. Seven hundred and thirty-six screws in 383 patients were identified. Fifty-five patients were excluded because of lack of data leaving 328 patients (188 male patients, NVP-BSK805 140 female patients) with 633 screws. Three hundred and thirty-nine pedicle, 154 transarticular, 63 laminar,
and 77 short pars screws were placed, and of the 509 screws with postoperative CT scans, accuracy rates (Types I and II) were 98.8%, 98.5%, 100%, and 94.6%, respectively. Eight were unacceptably placed: two medially and six encroaching on the vertebral artery foramen. One patient had a vertebral artery occlusion and another had a dissection. There were no neurologic injuries. Mean CT measurements of pedicle height, axial width, and laminar width were 8.1, 5.8, and 5.7 mm respectively, with males having significantly larger pedicle height (P < 0.001), pedicle width (P < 0.001), and laminar width (P < 0.022).
Conclusion. We show a lower than previously reported incidence of complications associated with posterior C2 screw placement. The multiple techniques of posterior C2 fixation available allow for flexibility in determining ideal technique.