225-0.45 μl/ml).21 Similar to our results, Figueiredo et al.37 found that the T. capitata essential oil, which is rich with carvacrol, was effective against Salmonella spp. and E. coli.37 De Martino et al.38 reported that essential oil components,

particularly phenols such as carvacrol and thymol, had good antimicrobial activity effects. Conclusion The T. syriacus essential oil and its components exhibited very good inhibitory effects against some Syrian gram-negative isolates in the present study. The most effective components were thymol, carvacrol, dihydro-carvon, and linalool, respectively. Inhibitors,research,lifescience,medical We recommend that the synergistic and antagonistic effects of these components be

further tested in future clinical trials. Acknowledgment The Inhibitors,research,lifescience,medical authors wish to thank the Director General of the AECS and the head of the Department of Molecular Biology and Biotechnology for their support. The authors would also like to thank Dr. M. Safi for his critical reading of this manuscript. Conflict of interest: None declared.
Background: We sought to determine the clinical characteristics of pediatric esophagitis in Inhibitors,research,lifescience,medical southern Iran. Methods: This cross-sectional study was conducted over a 4-year period, from 2005 to 2009, in Nemazee Hospital, a tertiary healthcare center in Shiraz, southern Iran. We consecutively included all pediatric patients (<18 years) who underwent endoscopy in our center Inhibitors,research,lifescience,medical and had pathology-confirmed diagnosis of esophagitis. Data regarding the patients’ demographic characteristics, comorbidities, and clinical findings were recorded using a questionnaire. All the patients underwent upper gastrointestinal endoscopy and biopsy of

the esophagus, and the findings were recorded in the questionnaire. Results: We studied 125 children, comprising 61 (48.8%) girls and 64 (51.2%) boys at a mean age of 6.6±5.5 years. Repeated vomiting was the prominent symptom in our series, with it being Inhibitors,research,lifescience,medical reported by 75 (60%) patients, followed by fever in 35 (28%). Erythema (33.6%), esophageal ulcer (11.2%), and whitish patch (8.0%) were the most common endoscopic findings, while reflux esophagitis (32.8%), chronic (6.4%) and acute esophagitis (5.6%), and candida esophagitis (5.6%) were the most common histological diagnoses. Only one (0.8%) patient was diagnosed as having secondly eosinophilic esophagitis, aspergillosis, and INCB28060 ic50 graft-versus-host disease. Conclusion: Reflux was the most common cause of esophagitis in the pediatric population of southern Iran. Contrary to previous reports, the prevalence of eosinophilic esophagitis was far less than that estimated, while the prevalence of opportunistic infections was higher secondary to post-liver transplantation immunosuppression.