Improvement in degree of overhydration and anthropometric markers TSF, BSF and MAC in MHD patients was associated with survival. WU CHIA-CHAO1,3, SU SUI-LUNG2, KAO SEN-YEONG2, LU KUO-CHENG3, LIN YUH-FENG4 1Division of Nephrology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center; 2School of Public Health, National Defense Medical Center; 3Division of Nephrology, Department of Medicine, Cardinal

Tien Hospital, School of Medicine, Fu Jen Catholic University; 4Division of Nephrology, Department of Medicine, Shuang Ho Hospital, see more Graduate Institute of Clinical Medicine, Taipei Medical University Introduction: Taiwan has ABT 263 the highest prevalence and incidence of end stage renal disease in the world. The majorities were

due to diabetes mellitus (DM) or hypertension (HTN). However, the characteristic risk factors for the development of chronic kidney disease (CKD) in each specific high risk population in Taiwan region are still unclear. This study surveyed the most common risk factors and identified their effects on CKD in general population or patients with HTN and/or DM in Taiwan. Methods: This study included 5328 cases and 5135 controls in CKD/HTN/DM outpatient department and health center of 10 hospitals from 2008 to 2010. Forteen common risk factors were surveyed (4 of demographic factors, 5 of disease factors and 5 of lifestyle factors) and checked their impact on CKD development. Variables with significant heterogeneity between patients with different Phloretin comorbidities were stratified analysed.

Results: Male, aging, low incomes, hyperuricemia and no exercise habits were risk factors of CKD; and their impact on people with different comorbidities were the same. Anemia also was a risk factor, and there was an additive effect between anemia and hypertension on CKD. The association between hyperlipidemia related factors and CKD was moderated by HTN; it was a significant risk factor in people without HTN but not in patient with HTN. Based on the power of this study, we considered that hepatitis B, smoking, alcohol intake and groundwater using might not the important risk factors of CKD. The associations between hepatitis C/betelnut chewing and CKD were needed to further research. Conclusion: Several risk factors in each specific high risk population had been identified in Taiwan. We considered that screening/preventing strategy on CKD in high risk patients might differ from health population. Further larger studies are needed for more strong statistical power.