Janssen funded the faculty meetings and meetings with practising psychiatrists that led to the development of the checklist

and also the work of ApotheCom ScopeMedical. Conflict of interest statement: The authors’ involvement in this initiative was part of paid consultancy work with Janssen, which also provided travel expenses for authors to attend group meetings where the checklist was developed. In addition, Inhibitors,research,lifescience,medical in the past 3 years all the authors except M.E.J.L. have received conference support and honoraria for lecturing and other consultancy work from Janssen and other pharmaceutical companies manufacturing antipsychotic drugs. PDE inhibitors high throughput screening During this period several authors have also received research grants from Janssen Inhibitors,research,lifescience,medical and/or other companies. Contributor Information Peter M Haddad, Greater

Manchester West Mental Health NHS Foundation Trust, Cromwell House, Cromwell Road, Eccles, Salford M30 OGT, UK. W Wolfgang Fleischhacker, Medical University Innsbruck, Innsbruck, Austria. Joseph Peuskens, Katholieke Universiteit Leuven, Kortenberg, Belgium. Roberto Cavallaro, Vita-Salute San Raffaele University, Milano, Italy. Michael EJ Lean, University Inhibitors,research,lifescience,medical of Glasgow, Inhibitors,research,lifescience,medical Glasgow, UK. Margarita Morozova, National Center of Mental Health, Russian Academy of Medical Science, Moscow, Russian Federation. Gavin Reynolds, Sheffield Hallam University, Sheffield, UK. Jean-Michel Azorin, Hôpital Sainte Marguerite, Marseille, France. Pierre Thomas, Université Lille Nord de France, Lille, France. Hans-Jürgen Möller, Ludwig Maximilians University, Munich, Germany.
Major depressive disorder

Inhibitors,research,lifescience,medical (MDD) is a mental disease characterized by reduced mood, low self-esteem and loss of interest or pleasure in Bay 11-7085 normally enjoyable activities. MDD is one of the most prevalent mood disorders; the National Comorbidity Survey (NCS) reported a lifetime prevalence of 16.2% and a 12-month prevalence of 6.6% in the US population [Kessler et al. 2005]. In Europe, the 12-month prevalence was estimated at 6.9% [Wittchen et al. 2011]. The World Health Organization (WHO) ranks depression as the fourth leading cause of disability worldwide [Murray and Lopez, 1996] and projects that it will be the second leading cause of disability by 2020 [Lopez and Murray, 1998]. MDD does not only affect mood. It has also been widely associated with deficits in cognition [Baudic et al. 2004; Beats et al. 1996; Grant et al. 2001; Maalouf et al.