This seasonal flow regulation largely favors water consumption in non-flood seasons, primarily for farming irrigation. In non-flood season, the difference between average daily water discharge at Huayuankou and Lijin

results mainly from water consumption loss. This value increased in a step-wise manner from 26 m3/s in 1950–1968 to 242 m3/s in 1969–1986 Adriamycin in vitro and 421 m3/s in 1987–1999, respectively, followed by a slight decrease of 384 m3/s in 2000–2011 (Table 2). This pattern can be explained by increasing water use favored by strengthening runoff regulations. The construction of large dams on the Huanghe has largely controlled the frequent floods on the lower reaches that are ded by monsoon rains. Long-term (1950–2011) PD0332991 datasheet observations of daily water discharge at Lijin reveal that peak flow > 6000 m3/s decreased dramatically from a total 155 days during 1950–1968 to 17 days during 1969–1986, and vanish completely since 1987 (Table 3). Even smaller flood peaks (4000–6000 m3/s) could not be observed after the construction of Xiaolangdi reservoir in 1999. Since 2000, low flow (<2000 m3/s) dominates the discharge pattern of the lower reaches most of the year, and flow >2000 m3/s is mainly concentrated within the annual WSM (often less than 20 days) when the released floodwater

is confined to <4000 m3/s. Huayuankou station recorded a similar trend, as shown in Table Axenfeld syndrome 3. Here, we select representative years (1954, 1988, 2003) to show the stepwise

drops in the amplitude of flood peaks recorded at Lijin and Huayuankou over time (Fig. 2). Both the Lijin and Huayuankou records show a similar pattern, with the amplitudes of flood peaks dramatically decreasing. At Huayuankou station, pre-dam discharge levels (1950–1960) show several flood peaks during the flood season, with extreme peaks approaching ∼17,000 m3/s (e.g. 1954, Fig. 2A). In 1988 smaller flood peaks (<7000 m3/s) could be observed (Fig. 2B). In 2003 (after Xiaolangdi Reservoir was constructed), flood peaks >4000 m3/s become non-existent, e.g. in 2003 (Fig. 2C). Since 1950, no catastrophic flooding has occurred in the lower reaches of the Huanghe, owing to the effect of the dams. Sediment sequestration is a common problem in many large reservoirs. This problem is particularly severe for the Huanghe owing to the high suspended sediment concentration. Spatially, the Longyangxia and Liujiaxia reservoirs have a minor effect in trapping sediment, since only a small fraction of the Huanghe sediment is sourced from its upper reaches. The Liujiaxia and Longyangxia annually trap only 0.53 × 108 m3 (average 1968–1997 level) and 0.16 × 108 m3 (average 1986–1997 level) of sediment, respectively (Peng and Chen, 2009). The Sanmenxia and Xiaolangdi reservoirs in the lower middle reaches have trapped large amounts of sediment since their operation. The Sanmenxia Reservoir, in particular, had lost 45.