Conclusion: The results
indicate that apigenin and luteolin inhibited UVA-induced collagenolytic MMP-1 production by interfering with Ca(2+)-dependent MAPKs and AP-1 signaling. They may thus be potentially useful in the prevention and treatment of skin photoaging. (c) 2010 Japanese Society for Investigative Dermatology. Published by Elsevier Ireland Ltd. All rights reserved.”
“This article explores the idea that epileptic activity may interfere with psychosocial functions and development in children. In an adult population with epilepsy, left hemispheric seizure focus predicts worse psychosocial functioning. The developmental aspects of these disturbances require further studies. We Studied self-report measures of cognitive (locus of control) and emotional (Beck Youth Inventories of Emotional and Social Impairment) functions in 30 children with partial epilepsy (6-15 years) and 60 healthy matched controls. Multivariate Prexasertib purchase statistics revealed significant lateralization effects, with left-sided foci (n = 15) leading to more external locus of control. Opposite to adults, the children with right hemispheric foci (n = 15) exhibited more emotional impairments (anger, disruptive behavior) than the left hemispheric group. The cognitive
and emotional dysfunctions in epilepsy may result from the interaction of focus lateralization and brain development. The cognitive disturbances beginning in childhood may
lead to the stronger emotional impairments observed in adults selleck chemicals with left hemispheric selleck inhibitor seizures. (C) 2009 Elsevier Inc. All rights reserved.”
“The phenomenological Gilbert-Landau-Lifshitz theory of magnetic damping in ordered magnetic materials has long served as the central model employed in the analysis of considerable experimental magnetic resonance data. The problem undertaken here is to formulate the microscopic basis of the model in terms of usual theory of irreversible transport embodied in the fluctuation-dissipation-response theorems. As an application of the general method we establish a rigorous relationship between magnetic damping and acoustic damping implicit in magnetoelastic models. (C) 2010 American Institute of Physics. [doi:10.1063/1.3330646]“
“Objective: To investigate the differential effects of fetal exposure to antiepileptic drugs (AEDs) on cognitive fluency and flexibility in a prospective sample of children.
Methods: This substudy of the Neurodevelopmental Effects of Antiepileptic Drugs investigation enrolled pregnant women with epilepsy on AED monotherapy (carbamazepine, lamotrigine, and valproate). Blinded to drug exposure, 54 children were tested for ability to generate ideas in terms of quantity (fluency/flexibility) and quality (originality). Forty-two children met inclusion criteria (mean age = 4.2 years, SD = 0.5) for statistical analyses of drug exposure group differences.