(C) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 113: 1042-1049, 2009″
“The ubiquitin/26S proteasome pathway plays a central role in the degradation of short-lived regulatory proteins, to control many cellular events.

To further understand this pathway, we focused on the RPT2 subunit of the 26S proteasome regulatory particle. The Arabidopsis genome contains two genes, AtRPT2a and AtRPT2b, which encode paralog molecules of the RPT2 subunit, with a difference of only three amino acids in the protein sequences. Both genes showed CH5424802 cell line similar mRNA accumulation patterns. However, the rpt2a mutant showed a specific phenotype of enlarged leaves caused by increased cell size, in correlation with increased ploidy. Detailed analyses revealed that cell expansion is increased in the rpt2a mutant by extended endoreduplication early in leaf development. The transcription of genes encoding cell cycle-related components, for DNA replication licensing and the G2/M phase, was also promoted in the rpt2a mutant, suggesting that extended endoreduplication was caused by increased DNA replication, and

disrupted regulation of the G2/M checkpoint, at the proliferation stage of leaf development.”
“D-naproxen was selected as the imprinted molecule. An original ultraviolet spectrum analysis method based ACY-1215 in vitro on proof of solvent effects was designed to verify the realization of the noncovalent self-assembly between naproxen and functional monomers under the influence of the solvents

with different nature. The facts proved that it is a more scientific way to effectively implement the pre-selection of functional monomer. Then, a series of molecular imprinted polymers (MIPs) were synthesized by different ratios of raw materials. These products were detected by infrared spectroscopy as well as adsorption experimentation to analyze their structure and performance. Meanwhile, the transmission electron microscopy (TEM) was first used to observe the morphology of MIPs, by which the pore-forming mechanism and the effect of the solvent (porogen) were investigated. The MIPs with morphology of different structure were also tested in the adsorption kinetics experiments to testify the influence of morphology factors on the materials’ adsorption properties. LM-1149 Through the evaluation of the imprinting efficiency, the best condition accessing to the preparation of highly efficient D-naproxen imprinted polymer was obtained. The apparent imprinting efficiency of the ultimate product was as high as 90.39%. (C) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 113: 1050-1062, 2009″
“Elongator is a histone acetyl-transferase complex consisting of six subunits, and is highly conserved in eukaryotic organisms. Here, we isolated two novel mutants, elp2 and elp6, during a genetic screening for ABA-hypersensitive Arabidopsis mutants. Map-based cloning identified ELP2 and ELP6, which encode the orthologs of the yeast Elongator subunits, ELP2 and ELP6, respectively.